Water → 2-[4-(tert-Butyl-dimethyl-silanyloxymethyl)-6-chloro-pyridin-2-ylamino]-thiazole-5-carbonitrile
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[SiH2:5][O:6][C:7]([c:8]1[cH:9][c:10]([NH2:15])[n:11][c:12]([Cl:14])[cH:13]1)([CH3:16])[CH3:17].[C:26](=[O:27])([O-:28])[O-:29].[Cl:18][c:19]1[s:20][c:21]([C:24]#[N:25])[cH:22][n:23]1.[Cs+:30].[Cs+:31].[O:32]1[CH2:33][CH2:34][O:35][CH2:36][CH2:37]1.[O:41]=[C:42]([CH:43]=[CH:44][c:45]1[cH:46][cH:47][cH:48][cH:49][cH:50]1)[CH:51]=[CH:52][c:53]1[cH:54][cH:55][cH:56][cH:57][cH:58]1.[O:59]=[C:60]([CH:61]=[CH:62][c:63]1[cH:64][cH:65][cH:66][cH:67][cH:68]1)[CH:69]=[CH:70][c:71]1[cH:72][cH:73][cH:74][cH:75][cH:76]1.[O:77]=[C:78]([CH:79]=[CH:80][c:81]1[cH:82][cH:83][cH:84][cH:85][cH:86]1)[CH:87]=[CH:88][c:89]1[cH:90][cH:91][cH:92][cH:93][cH:94]1.[OH2:38].[Pd:39].[Pd:40]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[SiH2:5][O:6][C:7]([c:8]1[cH:9][c:10]([NH:15][c:19]2[s:20][c:21]([C:24]#[N:25])[cH:22][n:23]2)[n:11][c:12]([Cl:14])[cH:13]1)([CH3:16])[CH3:17]Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-fd5d493ae17140e3aae6d195683e201d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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