Dichloromethane → 8-ethyl-N'-(5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-yl)-1,4-dioxaspiro[4.4]nonane-7-carbohydrazide

HRID 1231257Notes

Reaction equation

HRID 1231257 reaction equation
[CH2:22]([CH3:23])[CH:24]1[CH:25]([C:33](=[O:34])[OH:35])[CH2:26][C:27]2([O:28][CH2:29][CH2:30][O:31]2)[CH2:32]1.[Cl:60][CH2:61][Cl:62].[NH:1]([NH2:2])[c:3]1[n:4][c:5]2[c:6]([n:7][cH:8]1)[n:9]([S:12](=[O:13])(=[O:14])[c:15]1[cH:16][cH:17][c:18]([CH3:19])[cH:20][cH:21]1)[cH:10][cH:11]2.[P-:36]([F:37])([F:38])([F:39])([F:40])([F:41])[F:42].[n:43]1([O:44][C:45]([N:46]([CH3:47])[CH3:48])=[N+:49]([CH3:50])[CH3:51])[c:52]2[n:53][cH:54][cH:55][cH:56][c:57]2[n:58][n:59]1>>[NH:1]([NH:2][C:33]([CH:25]1[CH:24]([CH2:22][CH3:23])[CH2:32][C:27]2([CH2:26]1)[O:28][CH2:29][CH2:30][O:31]2)=[O:34])[c:3]1[n:4][c:5]2[c:6]([n:7][cH:8]1)[n:9]([S:12](=[O:13])(=[O:14])[c:15]1[cH:16][cH:17][c:18]([CH3:19])[cH:20][cH:21]1)[cH:10][cH:11]2

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 9886HexafluorophosphateHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 580098102-Hydrazinyl-5-tosyl-5H-pyrrolo[2,3-b]pyrazineHCID 585573038-Ethyl-1,4-dioxaspiro[4,4]nonane-7-carboxylic acid

Product 1

HCID 585573298-ethyl-N'-(5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-yl)-1,4-dioxaspiro[4.4]nonane-7-carbohydrazide

Sources & evidence

ORD record
ord-9ff1383f14524a59925765f71b44d5ad
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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