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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1231266Generated: October 26, 2026

1-Butanol → 2,6-Difluoro-N-{3-[5-[2-({trans-4-[(methylsulfonyl)amino]cyclohexyl}amino)-4-pyrimidinyl]-2-(1-pyrrolidinyl)-1,3-thiazol-4-yl]phenyl}benzenesulfonamide

https://huagongshe.com/reaction/1231266

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-ButanolHCID 263—
ReactantN-(4-aminocyclohexyl)methanesulfonamideHCID 18348422—
ReactantN-{3-[5-(2-Chloro-4-pyrimidinyl)-2-(1-pyrrolidinyl)-1,3-thiazol-4-yl]phenyl}-2,6-difluorobenzenesulfonamideHCID 57989807—
Product2,6-Difluoro-N-{3-[5-[2-({trans-4-[(methylsulfonyl)amino]cyclohexyl}amino)-4-pyrimidinyl]-2-(1-pyrrolidinyl)-1,3-thiazol-4-yl]phenyl}benzenesulfonamideHCID 57989703—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-02bd75094c814b2fb75d2784f4d67514
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)