3-Aminophenol → N4-(3,4-dimethoxyphenyl)-5-fluoro-N2-(3-hydroxyphenyl)-2,4-pyrimidinediamine
Reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([F:19])[c:6]([NH:8][c:9]2[cH:10][c:11]([O:17][CH3:18])[c:12]([O:15][CH3:16])[cH:13][cH:14]2)[n:7]1.[OH:20][c:21]1[cH:22][c:23]([NH2:24])[cH:25][cH:26][cH:27]1>>[c:2]1([NH:24][c:23]2[cH:22][c:21]([OH:20])[cH:27][cH:26][cH:25]2)[n:3][cH:4][c:5]([F:19])[c:6]([NH:8][c:9]2[cH:10][c:11]([O:17][CH3:18])[c:12]([O:15][CH3:16])[cH:13][cH:14]2)[n:7]1Participants
3
Sources & evidence
- ORD record
- ord-39222263137442b2a943bb725b73fb30
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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