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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1232062Generated: November 4, 2026

Water → 5-Chloro-3-[2-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-2-oxoethyl]-2-(4-methoxyphenyl)-2,3-dihydro-1H-isoindol-1-one

https://huagongshe.com/reaction/1232062

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
Reactant1,4-Dioxa-8-azaspiro(4.5)decaneHCID 67435—
ReactantDiethyl cyanophosphonateHCID 76257—
ReactantHCID 13935113HCID 13935113—
Product5-Chloro-3-[2-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-2-oxoethyl]-2-(4-methoxyphenyl)-2,3-dihydro-1H-isoindol-1-oneHCID 13655925—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-b5dfb0ce5b244d1694698a680fb4b250
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)