tert-Butyl [3-(6-amino-1-oxo-3,4-dihydroisoquinolin-2(1H)-yl)propyl]methylcarbamate → 1-{2-[{6-[(2-{3-[(tert-Butoxycarbonyl)(methyl)amino]propyl}-1-oxo-1,2,3,4-tetrahydroisoquinolin-6-yl)amino]hexanoyl}(methyl)amino]ethyl}piperidin-4-yl biphenyl-2-ylcarbamate
Reaction equation
[NH2:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[C:8](=[O:12])[N:7]([CH2:13][CH2:14][CH2:15][N:16]([C:17]([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23])[CH3:24])[CH2:6][CH2:5]2.[c:25]1(-[c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)[c:26]([NH:31][C:32]([O:33][CH:34]2[CH2:35][CH2:36][N:37]([CH2:40][CH2:41][N:42]([C:43]([CH2:44][CH2:45][CH2:46][CH2:47][CH:48]=[O:49])=[O:50])[CH3:51])[CH2:38][CH2:39]2)=[O:52])[cH:27][cH:28][cH:29][cH:30]1>>[NH:1]([c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[C:8](=[O:12])[N:7]([CH2:13][CH2:14][CH2:15][N:16]([C:17]([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23])[CH3:24])[CH2:6][CH2:5]2)[CH2:48][CH2:47][CH2:46][CH2:45][CH2:44][C:43]([N:42]([CH2:41][CH2:40][N:37]1[CH2:36][CH2:35][CH:34]([O:33][C:32]([NH:31][c:26]2[c:25](-[c:53]3[cH:54][cH:55][cH:56][cH:57][cH:58]3)[cH:30][cH:29][cH:28][cH:27]2)=[O:52])[CH2:39][CH2:38]1)[CH3:51])=[O:50]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-40a439840769493a8e446aa03264858f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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