Methyl 5-bromopyridine-2-carboxylate → 5-{3-Chloro-4-[3,3,3-trifluoro-2-hydroxy-1-methyl-2-(3-methyl-2-oxo-2,3-dihydro-benzooxazol-5-yl)-propyl]-phenyl}-pyridine-2-carboxylic acid methyl ester
Reaction equation
[CH3:36][O:37][C:38](=[O:39])[c:40]1[n:41][cH:42][c:43]([Br:46])[cH:44][cH:45]1.[Cl:1][c:2]1[c:3]([CH:17]([C:18]([C:19]([F:20])([F:21])[F:22])([OH:23])[c:24]2[cH:25][cH:26][c:27]3[c:28]([n:29]([CH3:33])[c:30](=[O:32])[o:31]3)[cH:34]2)[CH3:35])[cH:4][cH:5][c:6]([B:8]2[O:9][C:10]([CH3:11])([CH3:12])[C:13]([CH3:14])([CH3:15])[O:16]2)[cH:7]1>>[Cl:1][c:2]1[c:3]([CH:17]([C:18]([C:19]([F:20])([F:21])[F:22])([OH:23])[c:24]2[cH:25][cH:26][c:27]3[c:28]([n:29]([CH3:33])[c:30](=[O:32])[o:31]3)[cH:34]2)[CH3:35])[cH:4][cH:5][c:6](-[c:43]2[cH:42][n:41][c:40]([C:38]([O:37][CH3:36])=[O:39])[cH:45][cH:44]2)[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-ecd105d99e2a47aa8f90cdf20363b530
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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