Benzyl 2-methylpiperazine-1-carboxylate → Benzyl 4-{[5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-2-oxo-1,2,3,4-tetrahydroquinazolin-7-yl]methyl}-2-methylpiperazine-1-carboxylate

HRID 1232361Notes

Reaction equation

HRID 1232361 reaction equation
[C:29](=[O:30])([O:31][CH2:32][c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1)[N:39]1[CH:40]([CH3:45])[CH2:41][NH:42][CH2:43][CH2:44]1.[Cl:1][c:2]1[c:3](-[c:8]2[c:9]3[c:14]([cH:15][c:16]([CH:18]=[O:19])[cH:17]2)[N:13]([c:20]2[c:21]([Cl:27])[cH:22][cH:23][cH:24][c:25]2[Cl:26])[C:12](=[O:28])[NH:11][CH2:10]3)[cH:4][cH:5][cH:6][cH:7]1>>[Cl:1][c:2]1[c:3](-[c:8]2[c:9]3[c:14]([cH:15][c:16]([CH2:18][N:42]4[CH2:41][CH:40]([CH3:45])[N:39]([C:29](=[O:30])[O:31][CH2:32][c:33]5[cH:34][cH:35][cH:36][cH:37][cH:38]5)[CH2:44][CH2:43]4)[cH:17]2)[N:13]([c:20]2[c:21]([Cl:27])[cH:22][cH:23][cH:24][c:25]2[Cl:26])[C:12](=[O:28])[NH:11][CH2:10]3)[cH:4][cH:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 22507589Benzyl 2-methylpiperazine-1-carboxylateHCID 226481625-(2-Chlorophenyl)-1-(2,6-dichlorophenyl)-2-oxo-1,2,3,4-tetrahydroquinazoline-7-carbaldehyde

Product 1

HCID 22647930Benzyl 4-{[5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-2-oxo-1,2,3,4-tetrahydroquinazolin-7-yl]methyl}-2-methylpiperazine-1-carboxylate

Sources & evidence

ORD record
ord-22b0152493ee45f69e6c0f26e8ba7f8e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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