Dimethyl Sulfoxide → 1'-[3-(Methyloxy)-4-nitrophenyl]-1,4'-bipiperidine

HRID 1232381Notes

Reaction equation

HRID 1232381 reaction equation
[CH3:1][O:2][c:3]1[c:4]([N+:10](=[O:11])[O-:12])[cH:5][cH:6][c:7]([F:9])[cH:8]1.[CH3:31][S:32]([CH3:33])=[O:34].[K+:25].[K+:26].[N:13]1([CH:19]2[CH2:20][CH2:21][NH:22][CH2:23][CH2:24]2)[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18]1.[O-:27][C:28]([O-:29])=[O:30].[OH2:35]>>[CH3:1][O:2][c:3]1[c:4]([N+:10](=[O:11])[O-:12])[cH:5][cH:6][c:7]([N:22]2[CH2:21][CH2:20][CH:19]([N:13]3[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18]3)[CH2:24][CH2:23]2)[cH:8]1

Participants

7

Reactant 6

HCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 962WaterHCID 19660Carbonate IonHCID 786071,4'-BipiperidineHCID 27792505-Fluoro-2-nitroanisole

Product 1

HCID 587483781'-[3-(Methyloxy)-4-nitrophenyl]-1,4'-bipiperidine

Sources & evidence

ORD record
ord-b456ebee6d2949df90ab074898f76dd7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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