Dichloromethane → 1-Boc-piperidine-3-carboxaldehyde

HRID 1232420Notes

Reaction equation

HRID 1232420 reaction equation
[C:12](=[O:13])([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[N:19]1[CH2:20][CH:21]([CH2:25][OH:26])[CH2:22][CH2:23][CH2:24]1.[Cl:27][CH2:28][Cl:29].[O:1]=[Cr:2]([Cl:3])([O-:4])=[O:5].[nH+:6]1[cH:7][cH:8][cH:9][cH:10][cH:11]1>>[C:12](=[O:13])([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[N:19]1[CH2:20][CH:21]([CH:25]=[O:26])[CH2:22][CH2:23][CH2:24]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 2763851tert-Butyl 3-(hydroxymethyl)piperidine-1-carboxylateHCID 4989215PyridiniumHCID 178418299HCID 178418299, compound

Product 1

HCID 99644481-Boc-piperidine-3-carboxaldehyde

Sources & evidence

ORD record
ord-06132b3eefc44bd4a611d0e79e69df5d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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