Cyclohexanone → 8'-fluoro-5'-methoxy-1'H-spiro[cyclohexane-1,4'-quinazolin]-2'(3'H)-one
Reaction equation
[F:1][c:2]1[c:3]([NH:10][C:11](=[O:12])[NH2:13])[cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1.[O:14]=[C:15]1[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]1>>[F:1][c:2]1[c:3]2[c:4]([c:5]([O:8][CH3:9])[cH:6][cH:7]1)[C:15]1([NH:13][C:11](=[O:12])[NH:10]2)[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]1Participants
3
Sources & evidence
- ORD record
- ord-85e4dd2715a441ad8b5acf1cc1da83ec
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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