Acetone → 2,4-Difluoro-4'-(3-nitro-benzyloxy)-biphenyl

HRID 1232595Notes

Reaction equation

HRID 1232595 reaction equation
[Br:1][CH2:2][c:3]1[cH:4][c:5]([N+:9](=[O:10])[O-:11])[cH:6][cH:7][cH:8]1.[C:27](=[O:28])([O-:29])[O-:30].[CH3:33][C:34](=[O:35])[CH3:36].[F:12][c:13]1[c:14](-[c:20]2[cH:21][cH:22][c:23]([OH:26])[cH:24][cH:25]2)[cH:15][cH:16][c:17]([F:19])[cH:18]1.[K+:31].[K+:32]>>[CH2:2]([c:3]1[cH:4][c:5]([N+:9](=[O:10])[O-:11])[cH:6][cH:7][cH:8]1)[O:26][c:23]1[cH:22][cH:21][c:20](-[c:14]2[c:13]([F:12])[cH:18][c:17]([F:19])[cH:16][cH:15]2)[cH:25][cH:24]1

Participants

6

Reactant 5

HCID 180AcetoneHCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 77568Benzene, 1-(bromomethyl)-3-nitro-HCID 1009552',4'-Difluoro(1,1'-biphenyl)-4-ol

Product 1

HCID 582877952,4-Difluoro-4'-(3-nitro-benzyloxy)-biphenyl

Sources & evidence

ORD record
ord-33718a795919496aaae96343a63ac999
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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