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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1233185Generated: October 31, 2026

Acetic Acid → 4-(4-Bromophenyl)-3-[3-(tert-butyldimethylsilanyloxy)-3-(4-fluorophenyl)propyl]-1-(4-fluorophenyl)azetidin-2-one

https://huagongshe.com/reaction/1233185

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantWaterHCID 962—
Reactanttert-Butyl methyl etherHCID 15413—
ReactantFluoride IonHCID 28179—
ReactantTributylammoniumHCID 3724478—
ReactantBistrimethylsilylacetamidHCID 11708267—
Reactant3-[2-[(4-Bromophenyl)-(4-fluorophenylamino)methyl]-5-(tert-butyl-dimethylsilanyloxy)-5-(4-fluorophenyl)pentanoyl]-4-phenyloxazolidin-2-oneHCID 22252067—
Product4-(4-Bromophenyl)-3-[3-(tert-butyldimethylsilanyloxy)-3-(4-fluorophenyl)propyl]-1-(4-fluorophenyl)azetidin-2-oneHCID 22252077—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-1fabdc9cb6ba4d65ab50c8f5d0a2ddbe
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)