Dimethyl Sulfoxide → Tert-butyl 4-(2-bromothieno[3,2-c]pyridin-4-yl)-1,4-diazepane-1-carboxylate

HRID 1233358Notes

Reaction equation

HRID 1233358 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([Cl:11])[n:6][cH:7][cH:8][c:9]2[s:10]1.[CH3:32][S:33]([CH3:34])=[O:35].[K+:12].[K+:13].[N:18]1([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:19][CH2:20][NH:21][CH2:22][CH2:23][CH2:24]1.[O-:14][C:15]([O-:16])=[O:17]>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([N:21]3[CH2:20][CH2:19][N:18]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:24][CH2:23][CH2:22]3)[n:6][cH:7][cH:8][c:9]2[s:10]1

Participants

6

Reactant 5

HCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 2756058Tert-butyl 1,4-diazepane-1-carboxylateHCID 177503902-Bromo-4-chlorothieno(3,2-c)pyridine

Product 1

HCID 67157246Tert-butyl 4-(2-bromothieno[3,2-c]pyridin-4-yl)-1,4-diazepane-1-carboxylate

Sources & evidence

ORD record
ord-665d66b71f27406faff0deba14545785
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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