4-Bromobenzyl bromide → 1'-(4-bromobenzyl)-5,6-difluorospiro[1-benzofuran-3,3'-indol]-2'(1'H)-one
Reaction equation
[Br:10][CH2:11][c:12]1[o:13][c:14]([C:15]([F:16])([F:17])[F:18])[cH:19][cH:20]1.[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][Br:7])[cH:8][cH:9]1.[CH3:41][c:42]1[c:43]2[cH:44][c:45]3[c:58]([cH:59][c:60]2[o:61][n:62]1)[O:57][CH2:56][C:46]31[c:47]2[c:48]([cH:49][cH:50][cH:51][cH:52]2)[NH:53][C:54]1=[O:55].[F:21][c:22]1[c:23]([F:40])[cH:24][c:25]2[c:26]([cH:39]1)[C:27]1([CH2:28][O:29]2)[C:30](=[O:38])[NH:31][c:32]2[cH:33][cH:34][cH:35][cH:36][c:37]21>>[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][N:31]2[C:30](=[O:38])[C:27]3([c:26]4[c:25]([cH:24][c:23]([F:40])[c:22]([F:21])[cH:39]4)[O:29][CH2:28]3)[c:37]3[c:32]2[cH:33][cH:34][cH:35][cH:36]3)[cH:8][cH:9]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-b7bb99f8b5504626a8707e4f0ca3b0af
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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