Potassium Cation → 4-(4-methoxyphenyl)-2,2-dimethyl-5-(4-(quinolin-2-ylmethoxy)phenyl)furan-3(2H)-one

HRID 1233928Notes

Reaction equation

HRID 1233928 reaction equation
[CH3:42][C:43]#[N:44].[Cl:30][CH2:31][c:32]1[n:33][c:34]2[cH:35][cH:36][cH:37][cH:38][c:39]2[cH:40][cH:41]1.[K+:24].[K+:25].[O-:26][C:27]([O-:28])=[O:29].[OH:1][c:2]1[cH:3][cH:4][c:5]([C:8]2=[C:9]([c:16]3[cH:17][cH:18][c:19]([O:22][CH3:23])[cH:20][cH:21]3)[C:10](=[O:15])[C:11]([CH3:13])([CH3:14])[O:12]2)[cH:6][cH:7]1>>[O:1]([c:2]1[cH:3][cH:4][c:5]([C:8]2=[C:9]([c:16]3[cH:17][cH:18][c:19]([O:22][CH3:23])[cH:20][cH:21]3)[C:10](=[O:15])[C:11]([CH3:13])([CH3:14])[O:12]2)[cH:6][cH:7]1)[CH2:31][c:32]1[n:33][c:34]2[cH:35][cH:36][cH:37][cH:38][c:39]2[cH:40][cH:41]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6342AcetonitrileHCID 19660Carbonate IonHCID 203942-(Chloromethyl)quinolineHCID 593547485-(4-hydroxyphenyl)-4-(4-methoxyphenyl)-2,2-dimethylfuran-3(2H)-one

Product 1

HCID 593548134-(4-methoxyphenyl)-2,2-dimethyl-5-(4-(quinolin-2-ylmethoxy)phenyl)furan-3(2H)-one

Sources & evidence

ORD record
ord-bfa53e8ca1e0482d8e7d9b855831e008
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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