3-(5-Bromo-2-methyl-thiophen-3-yl)-propionitrile → 4-Amino-2-[4-(2-cyanoethyl)-5-methylthiophen-2-yl]-thieno[3,2-c]pyridine-7-carboxylic acid amide

HRID 1234104Notes

Reaction equation

HRID 1234104 reaction equation
[Br:15][c:16]1[cH:17][c:18]([CH2:22][CH2:23][C:24]#[N:25])[c:19]([CH3:21])[s:20]1.[NH2:1][c:2]1[n:3][cH:4][c:5]([C:12](=[O:13])[NH2:14])[c:6]2[c:7]1[cH:8][c:9]([Br:11])[s:10]2>>[NH2:1][c:2]1[n:3][cH:4][c:5]([C:12](=[O:13])[NH2:14])[c:6]2[c:7]1[cH:8][c:9](-[c:16]1[cH:17][c:18]([CH2:22][CH2:23][C:24]#[N:25])[c:19]([CH3:21])[s:20]1)[s:10]2

Participants

3

Reactant 2

HCID 184465373-(5-Bromo-2-methyl-thiophen-3-yl)-propionitrileHCID 588407134-Amino-2-Bromothieno[3,2-C]pyridine-7-Carboxamide

Product 1

HCID 588407374-Amino-2-[4-(2-cyanoethyl)-5-methylthiophen-2-yl]-thieno[3,2-c]pyridine-7-carboxylic acid amide

Sources & evidence

ORD record
ord-51203e4f3d0d463bb9efb1a63372c833
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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