HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1234106Generated: November 2, 2026
Tetrahydrofuran → diethyl 2-(4-amino-3-chloro-5-trifluoromethyl-benzyl)-2-{2-oxo-2-[4-(2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin-1-yl]-ethyl}-malonate
https://huagongshe.com/reaction/1234106
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Tetrafluoroborate | HCID 26255 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | O-benzotriazol-1-yl-tetramethyluronium | HCID 130500 | — |
| Reactant | 3-(Piperidin-4-yl)-3,4-dihydroquinazolin-2(1H)-one | HCID 11042597 | — |
| Reactant | 4-(4-Amino-3-chloro-5-trifluoromethyl-phenyl)-3,3-bis-ethoxycarbonyl-butanoic acid | HCID 22184613 | — |
| Product | diethyl 2-(4-amino-3-chloro-5-trifluoromethyl-benzyl)-2-{2-oxo-2-[4-(2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin-1-yl]-ethyl}-malonate | HCID 68592549 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (5/10) |
|---|
| ORD ID | ord-9f091cf9bd2548bba274ffea955f2a70 |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (5/10) |
|---|
