Ethylene Glycol → 4-[7-(2-Hydroxy-ethoxy)-quinazolin-4-yl]-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:11]([CH3:12])([CH3:13])([CH3:14])[O:15][C:16](=[O:17])[N:18]1[CH2:19][CH2:20][CH:21]([c:24]2[n:25][cH:26][n:27][c:28]3[cH:29][c:30]([F:34])[cH:31][cH:32][c:33]23)[CH2:22][CH2:23]1.[CH3:1][C:2]([CH3:3])([O-:4])[CH3:5].[CH3:35][S:36]([CH3:37])=[O:38].[K+:6].[Na+:43].[O-:39][C:40]([OH:41])=[O:42].[OH:7][CH2:8][CH2:9][OH:10]>>[O:7]([CH2:8][CH2:9][OH:10])[c:30]1[cH:29][c:28]2[n:27][cH:26][n:25][c:24]([CH:21]3[CH2:20][CH2:19][N:18]([C:16]([O:15][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:17])[CH2:23][CH2:22]3)[c:33]2[cH:32][cH:31]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-2a418dfcd7d64928899697856d25b40a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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