4-Chloro-3-(1-methyl-pyrrolidin-2-ylmethoxy)-phenylamine → [4-Chloro-3-(1-methyl-pyrrolidin-2-ylmethoxy)-phenyl]-[7-(2-methoxy-phenyl)-pyrrolo[2,1-f][1,2,4]triazin-2-yl]-amine

HRID 1234679Notes

Reaction equation

HRID 1234679 reaction equation
[CH3:17][O:18][c:19]1[c:20](-[c:25]2[cH:26][cH:27][c:28]3[cH:29][n:30][c:31]([O:34][S:35]([C:36]([F:37])([F:38])[F:39])(=[O:40])=[O:41])[n:32][n:33]23)[cH:21][cH:22][cH:23][cH:24]1.[Cl:1][c:2]1[c:3]([O:9][CH2:10][CH:11]2[N:12]([CH3:16])[CH2:13][CH2:14][CH2:15]2)[cH:4][c:5]([NH2:8])[cH:6][cH:7]1>>[Cl:1][c:2]1[c:3]([O:9][CH2:10][CH:11]2[N:12]([CH3:16])[CH2:13][CH2:14][CH2:15]2)[cH:4][c:5]([NH:8][c:31]2[n:30][cH:29][c:28]3[cH:27][cH:26][c:25](-[c:20]4[c:19]([O:18][CH3:17])[cH:24][cH:23][cH:22][cH:21]4)[n:33]3[n:32]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 540900204-Chloro-3-(1-methyl-pyrrolidin-2-ylmethoxy)-phenylamineHCID 86661678Trifluoro-methanesulfonic acid 7-(2-methoxy-phenyl)-pyrrolo[2,1-f][1,2,4]triazin-2-yl ester

Product 1

HCID 66711870[4-Chloro-3-(1-methyl-pyrrolidin-2-ylmethoxy)-phenyl]-[7-(2-methoxy-phenyl)-pyrrolo[2,1-f][1,2,4]triazin-2-yl]-amine

Sources & evidence

ORD record
ord-b1373a197a7142fd914d327ed8dc5901
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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