Carbonate Ion → Methyl 2-(6-{[(ethylamino)carbonyl]amino}pyridin-3-yl)-1,3-thiazole-5-carboxylate

HRID 1234750Notes

Reaction equation

HRID 1234750 reaction equation
[Br:22][c:23]1[s:24][c:25]([C:28](=[O:29])[O:30][CH3:31])[cH:26][n:27]1.[C:32](=[O:33])([O-:34])[O-:35].[CH2:1]([CH3:2])[NH:3][C:4](=[O:5])[NH:6][c:7]1[n:8][cH:9][c:10]([B:13]2[O:14][C:15]([CH3:16])([CH3:17])[C:18]([CH3:19])([CH3:20])[O:21]2)[cH:11][cH:12]1.[Cs+:36].[Cs+:37]>>[CH2:1]([CH3:2])[NH:3][C:4](=[O:5])[NH:6][c:7]1[n:8][cH:9][c:10](-[c:23]2[s:24][c:25]([C:28](=[O:29])[O:30][CH3:31])[cH:26][n:27]2)[cH:11][cH:12]1

Participants

5

Reactant 4

HCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 2773502Methyl 2-bromothiazole-5-carboxylateHCID 592084346-(3-Ethylureido)pyridine-3-boronic acid pinacol ester

Product 1

HCID 59208451Methyl 2-(6-{[(ethylamino)carbonyl]amino}pyridin-3-yl)-1,3-thiazole-5-carboxylate

Sources & evidence

ORD record
ord-cd463ec99e324236b975daa0321d1b54
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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