Bicarbonate Ion → 7-(2-Fluoro-4-nitrophenoxy)-2-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)thieno[3,2-b]pyridine

HRID 1234975Notes

Reaction equation

HRID 1234975 reaction equation
[Br:22][c:23]1[cH:24][c:25]2[n:26][cH:27][cH:28][c:29]([O:32][c:33]3[c:34]([F:42])[cH:35][c:36]([N+:39](=[O:40])[O-:41])[cH:37][cH:38]3)[c:30]2[s:31]1.[CH3:48][O:49][CH2:50][CH2:51][O:52][CH3:53].[F:1][C:2]([F:3])([F:4])[S:5]([O:6][C:7]1=[CH:12][CH2:11][N:10]([CH3:13])[CH2:9][CH2:8]1)(=[O:14])=[O:15].[K+:16].[K+:17].[Na+:47].[O-:18][C:19]([O-:20])=[O:21].[O-:43][C:44]([OH:45])=[O:46].[OH2:54].[cH:55]1[cH:56][cH:57][c:58]([P:59]([Pd:60]([P:61]([c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)([c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)[c:74]2[cH:75][cH:76][cH:77][cH:78][cH:79]2)([P:80]([c:81]2[cH:82][cH:83][cH:84][cH:85][cH:86]2)([c:87]2[cH:88][cH:89][cH:90][cH:91][cH:92]2)[c:93]2[cH:94][cH:95][cH:96][cH:97][cH:98]2)[P:99]([c:100]2[cH:101][cH:102][cH:103][cH:104][cH:105]2)([c:106]2[cH:107][cH:108][cH:109][cH:110][cH:111]2)[c:112]2[cH:113][cH:114][cH:115][cH:116][cH:117]2)([c:118]2[cH:119][cH:120][cH:121][cH:122][cH:123]2)[c:124]2[cH:125][cH:126][cH:127][cH:128][cH:129]2)[cH:130][cH:131]1>>[C:7]1([c:23]2[cH:24][c:25]3[n:26][cH:27][cH:28][c:29]([O:32][c:33]4[c:34]([F:42])[cH:35][c:36]([N+:39](=[O:40])[O-:41])[cH:37][cH:38]4)[c:30]3[s:31]2)=[CH:12][CH2:11][N:10]([CH3:13])[CH2:9][CH2:8]1

Participants

10

Reactant 9

HCID 769Bicarbonate IonHCID 813Potassium Cation2×HCID 923Sodium ionHCID 962WaterHCID 80711,2-DimethoxyethaneHCID 19660Carbonate IonHCID 113795771-Methyl-1,2,3,6-tetrahydropyridin-4-yl trifluoromethanesulfonateHCID 594245212-Bromo-7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridineHCID 178420554HCID 178420554, compound

Product 1

HCID 594577227-(2-Fluoro-4-nitrophenoxy)-2-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)thieno[3,2-b]pyridine

Sources & evidence

ORD record
ord-051434932cfc488885ea68c9368583b7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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