Ethanol → (1RS,2SR)-2-amino-3-(4-fluorophenyl)-1-(4-(trifluoromethyl)phenyl)-1-propanol

HRID 1235379Notes

Reaction equation

HRID 1235379 reaction equation
[CH3:27][CH2:28][OH:29].[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][CH:9]2[NH:10][C:11](=[O:24])[O:12][CH:13]2[c:14]2[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]2)[cH:6][cH:7]1.[Na+:26].[OH-:25]>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][CH:9]([NH2:10])[CH:13]([OH:12])[c:14]2[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 702EthanolHCID 923Sodium ionHCID 961HydroxideHCID 22261770(4RS,5SR)-4-((4-fluorophenyl)methyl)-5-(4-(trifluoromethyl)phenyl)-1,3-oxazolidin-2-one

Product 1

HCID 22261902(1RS,2SR)-2-amino-3-(4-fluorophenyl)-1-(4-(trifluoromethyl)phenyl)-1-propanol

Sources & evidence

ORD record
ord-d19329cb74b14874a79daeb9391865e9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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