Dimethyl Sulfoxide → Ethyl 5-chloro-2-methyl-3-phenyl-2H-isoindole-1-carboxylate

HRID 1235911Notes

Reaction equation

HRID 1235911 reaction equation
[C:22](=[O:23])([O-:24])[O-:25].[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[nH:7][c:8](-[c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[c:9]2[cH:10][c:11]([Cl:15])[cH:12][cH:13][c:14]12.[CH3:28][I:29].[CH3:30][S:31]([CH3:32])=[O:33].[K+:26].[K+:27]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[n:7]([CH3:22])[c:8](-[c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[c:9]2[cH:10][c:11]([Cl:15])[cH:12][cH:13][c:14]12

Participants

6

Reactant 5

HCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 6328Methyl iodideHCID 19660Carbonate IonHCID 54174784Ethyl 5-chloro-3-phenyl-2H-isoindole-1-carboxylate

Product 1

HCID 54012509Ethyl 5-chloro-2-methyl-3-phenyl-2H-isoindole-1-carboxylate

Sources & evidence

ORD record
ord-d312c8c4d91a470cbdd2d606b20b91fa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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