3-Amino-1,1,1-trifluoro-2-methylpropan-2-ol → 3-Amino-6-(1-methyl-1H-pyrazol-4-yl)-N-(3,3,3-trifluoro-2-hydroxy-2-methylpropyl)-5-(trifluoromethyl)picolinamide

HRID 1236184Notes

Reaction equation

HRID 1236184 reaction equation
[NH2:1][c:2]1[c:3]([C:18](=[O:19])[OH:20])[n:4][c:5](-[c:12]2[cH:13][n:14][n:15]([CH3:17])[cH:16]2)[c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1.[NH2:21][CH2:22][C:23]([C:24]([F:25])([F:26])[F:27])([OH:28])[CH3:29]>>[NH2:1][c:2]1[c:3]([C:18](=[O:19])[NH:21][CH2:22][C:23]([C:24]([F:25])([F:26])[F:27])([OH:28])[CH3:29])[n:4][c:5](-[c:12]2[cH:13][n:14][n:15]([CH3:17])[cH:16]2)[c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1

Participants

3

Reactant 2

HCID 136207593-Amino-1,1,1-trifluoro-2-methylpropan-2-olHCID 673832773-Amino-6-(1-methyl-1H-pyrazol-4-yl)-5-(trifluoromethyl)picolinic acid

Product 1

HCID 534723863-Amino-6-(1-methyl-1H-pyrazol-4-yl)-N-(3,3,3-trifluoro-2-hydroxy-2-methylpropyl)-5-(trifluoromethyl)picolinamide

Sources & evidence

ORD record
ord-536291b6e4eb438d8e5cecf16e20f42d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…