Bromide ion → N-(4-chloro-3-(pyridin-2-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide

HRID 1236412Notes

Reaction equation

HRID 1236412 reaction equation
[Br-:23].[Cl:1][c:2]1[c:3]([I:22])[cH:4][c:5]([NH:8][C:9](=[O:10])[c:11]2[c:12]([CH3:21])[n:13][c:14]([C:17]([F:18])([F:19])[F:20])[cH:15][cH:16]2)[cH:6][cH:7]1.[n:24]1[c:25]([Zn+:30])[cH:26][cH:27][cH:28][cH:29]1>>[Cl:1][c:2]1[c:3](-[c:25]2[n:24][cH:29][cH:28][cH:27][cH:26]2)[cH:4][c:5]([NH:8][C:9](=[O:10])[c:11]2[c:12]([CH3:21])[n:13][c:14]([C:17]([F:18])([F:19])[F:20])[cH:15][cH:16]2)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 259Bromide ionHCID 66877122N-(4-Chloro-3-iodophenyl)-6-(trifluoromethyl)-2-methylpyridine-3-carboxamideHCID 178528054HCID 178528054, compound

Product 1

HCID 44626323N-(4-chloro-3-(pyridin-2-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide

Sources & evidence

ORD record
ord-36d8db5fbb5547258270282322d28e5a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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