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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1236519Generated: October 25, 2026

Hydrochloric Acid → {2-Oxo-2-[4-(2-trifluoromethyl-benzoyl)-piperazin-1-yl]-ethyl}-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/1236519

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantN-(tert-butoxycarbonyl)glycineHCID 78288—
ReactantDiisopropylethylamineHCID 81531—
Reactant1-[2-(Trifluoromethyl)benzoyl]piperazineHCID 16733784—
Product{2-Oxo-2-[4-(2-trifluoromethyl-benzoyl)-piperazin-1-yl]-ethyl}-carbamic acid tert-butyl esterHCID 59559599—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-f5e7437b33c94e30a583f906d68aefa4
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)