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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1236901Generated: October 31, 2026

Hydrochloric Acid → Methyl 5-[2-amino-5-[(4-methylpiperazin-1-yl)methyl]anilino]-3-[1-[2-(trifluoromethyl)phenyl]ethoxy]thiophene-2-carboxylate

https://huagongshe.com/reaction/1236901

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantTolueneHCID 1140—
ReactantTrimethyl orthoformateHCID 9005—
ReactantHCID 74944122HCID 74944122—
ProductMethyl 5-[2-amino-5-[(4-methylpiperazin-1-yl)methyl]anilino]-3-[1-[2-(trifluoromethyl)phenyl]ethoxy]thiophene-2-carboxylateHCID 76559482—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-981dc9b1893b4085a6d6d51e86113c1e
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)