Potassium Cation → 4-[1-(trans-4-{[tert-butyl(dimethyl)silyl]oxy}cyclohexyl)-1H-pyrazol-4-yl]-2-chloro-N-methylfuro[2,3-c]pyridin-7-amine

HRID 1237408Notes

Reaction equation

HRID 1237408 reaction equation
[C:14]([CH3:15])([CH3:16])([CH3:17])[Si:18]([O:19][CH:20]1[CH2:21][CH2:22][CH:23]([n:26]2[n:27][cH:28][c:29]([B:31]3[O:32][C:33]([CH3:34])([CH3:35])[C:36]([CH3:37])([CH3:38])[O:39]3)[cH:30]2)[CH2:24][CH2:25]1)([CH3:40])[CH3:41].[C:42](=[O:43])([O-:44])[O-:45].[CH2:48]1[O:49][CH2:50][CH2:51][O:52][CH2:53]1.[Cl:1][c:2]1[cH:3][c:4]2[c:5]([c:6]([NH:11][CH3:12])[n:7][cH:8][c:9]2[I:10])[o:13]1.[K+:46].[K+:47].[OH2:54]>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([c:6]([NH:11][CH3:12])[n:7][cH:8][c:9]2-[c:29]2[cH:28][n:27][n:26]([CH:23]3[CH2:22][CH2:21][CH:20]([O:19][Si:18]([C:14]([CH3:15])([CH3:16])[CH3:17])([CH3:40])[CH3:41])[CH2:25][CH2:24]3)[cH:30]2)[o:13]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 66759889HCID 66759889, compoundHCID 667600401-[trans-4-[(tert-butyldimethylsilyl)oxy]cyclohexyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Product 1

HCID 667607324-[1-(trans-4-{[tert-butyl(dimethyl)silyl]oxy}cyclohexyl)-1H-pyrazol-4-yl]-2-chloro-N-methylfuro[2,3-c]pyridin-7-amine

Sources & evidence

ORD record
ord-1ae486d76b8440a8a0f906b4bb2e9439
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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