3-Thiophenecarboxaldehyde → 4-tert-butyl-N-[3-[(4-methoxybenzoyl)amino]-4-pyridinyl]-2-[1-(thiophen-3-ylmethyl)piperidin-4-yl]oxybenzamide

HRID 1237784Notes

Reaction equation

HRID 1237784 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]([O:31][CH:32]2[CH2:33][CH2:34][NH:35][CH2:36][CH2:37]2)[c:8]([C:9](=[O:10])[NH:11][c:12]2[c:13]([NH:18][C:19]([c:20]3[cH:21][cH:22][c:23]([O:26][CH3:27])[cH:24][cH:25]3)=[O:28])[cH:14][n:15][cH:16][cH:17]2)[cH:29][cH:30]1.[s:38]1[cH:39][c:40]([CH:43]=[O:44])[cH:41][cH:42]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]([O:31][CH:32]2[CH2:33][CH2:34][N:35]([CH2:43][c:40]3[cH:39][s:38][cH:42][cH:41]3)[CH2:36][CH2:37]2)[c:8]([C:9](=[O:10])[NH:11][c:12]2[c:13]([NH:18][C:19]([c:20]3[cH:21][cH:22][c:23]([O:26][CH3:27])[cH:24][cH:25]3)=[O:28])[cH:14][n:15][cH:16][cH:17]2)[cH:29][cH:30]1

Participants

3

Reactant 2

HCID 681353-ThiophenecarboxaldehydeHCID 11576987N4-[4-tert-butyl-2-(piperidin-4-yloxy)benzoyl]-N3-(4-methoxybenzoyl)-3,4-pyridinediamine

Product 1

HCID 115852024-tert-butyl-N-[3-[(4-methoxybenzoyl)amino]-4-pyridinyl]-2-[1-(thiophen-3-ylmethyl)piperidin-4-yl]oxybenzamide

Sources & evidence

ORD record
ord-a1e94d930dd9420c9204d0fba1b4c0bb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…