Ethyl 2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanoate → Ethyl 2-[4-[4-[4-[1-(2-fluorophenyl)ethoxycarbonylamino]-3-methyl-1,2-oxazol-5-yl]-2-methylphenyl]phenyl]propanoate

HRID 1237917Notes

Reaction equation

HRID 1237917 reaction equation
[CH2:28]([CH3:29])[O:30][C:31]([CH:32]([CH3:33])[c:34]1[cH:35][cH:36][c:37]([B:40]2[O:41][C:42]([CH3:43])([CH3:44])[C:45]([CH3:46])([CH3:47])[O:48]2)[cH:38][cH:39]1)=[O:49].[F:1][c:2]1[c:3]([CH:8]([CH3:9])[O:10][C:11]([NH:12][c:13]2[c:14]([CH3:26])[n:15][o:16][c:17]2-[c:18]2[cH:19][c:20]([CH3:25])[c:21]([Br:24])[cH:22][cH:23]2)=[O:27])[cH:4][cH:5][cH:6][cH:7]1>>[F:1][c:2]1[c:3]([CH:8]([CH3:9])[O:10][C:11]([NH:12][c:13]2[c:14]([CH3:26])[n:15][o:16][c:17]2-[c:18]2[cH:19][c:20]([CH3:25])[c:21](-[c:37]3[cH:36][cH:35][c:34]([CH:32]([C:31]([O:30][CH2:28][CH3:29])=[O:49])[CH3:33])[cH:39][cH:38]3)[cH:22][cH:23]2)=[O:27])[cH:4][cH:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 58539349Ethyl 2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanoateHCID 761917711-(2-fluorophenyl)ethyl N-[5-(4-bromo-3-methylphenyl)-3-methyl-1,2-oxazol-4-yl]carbamate

Product 1

HCID 67352634Ethyl 2-[4-[4-[4-[1-(2-fluorophenyl)ethoxycarbonylamino]-3-methyl-1,2-oxazol-5-yl]-2-methylphenyl]phenyl]propanoate

Sources & evidence

ORD record
ord-1fb8cc5a9ddd472cb5be42149c5b6fa6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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