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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1238023Generated: October 25, 2026

Hydrochloric Acid → 4-(4-Chloro-2-fluoro-5-hydroxy-phenylamino)-7-(3-chloro-propoxy)-6-methoxy-quinoline-3-carbonitrile

https://huagongshe.com/reaction/1238023

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantPyridineHCID 1049—
ReactantGlycol monoethyl etherHCID 8076—
Reactant5-Amino-2-chloro-4-fluorophenolHCID 158654—
ReactantMethylcarbonateHCID 4585885—
Reactant4-Chloro-7-(3-chloropropoxy)-6-methoxyquinoline-3-carbonitrileHCID 11220637—
Product4-(4-Chloro-2-fluoro-5-hydroxy-phenylamino)-7-(3-chloro-propoxy)-6-methoxy-quinoline-3-carbonitrileHCID 22466591—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-d9bf7a5f001648c3b96fde3842c6c30f
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)