1-(3-Fluorobenzyl)-1H-indazol-5-amine → Ethyl 4-{[1-(3-fluorobenzyl)-1H-indazol-5-yl]amino}-5,7-dihydro-6H-pyrrolo[3',4':4,5]thieno[2,3-d]pyrimidine-6-carboxylate

HRID 1238104Notes

Reaction equation

HRID 1238104 reaction equation
[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[s:8][c:9]1[c:10]2[CH2:11][N:12]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[CH2:13]1.[F:19][c:20]1[cH:21][c:22]([CH2:23][n:24]2[n:25][cH:26][c:27]3[cH:28][c:29]([NH2:33])[cH:30][cH:31][c:32]23)[cH:34][cH:35][cH:36]1>>[c:2]1([NH:33][c:29]2[cH:28][c:27]3[cH:26][n:25][n:24]([CH2:23][c:22]4[cH:21][c:20]([F:19])[cH:36][cH:35][cH:34]4)[c:32]3[cH:31][cH:30]2)[c:3]2[c:4]([n:5][cH:6][n:7]1)[s:8][c:9]1[c:10]2[CH2:11][N:12]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[CH2:13]1

Participants

3

Reactant 2

HCID 71470731-(3-Fluorobenzyl)-1H-indazol-5-amineHCID 58116864Ethyl12-chloro-7-thia-4,9,11-triazatricyclo[6.4.0.02,6]dodeca-1(8),2(6),9,11-tetraene-4-carboxylate

Product 1

HCID 58116971Ethyl 4-{[1-(3-fluorobenzyl)-1H-indazol-5-yl]amino}-5,7-dihydro-6H-pyrrolo[3',4':4,5]thieno[2,3-d]pyrimidine-6-carboxylate

Sources & evidence

ORD record
ord-5e43de90e0754e48aa31f9b321b8a48c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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