5-[3,5-Bis(trifluoromethyl)phenyl]-3-(chloromethyl)-1,2,4-oxadiazole → 1-({5-[3,5-bis(Trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-4-chloro-2-(trifluoromethyl)-1H-indole-5-carbonitrile

HRID 1238258Notes

Reaction equation

HRID 1238258 reaction equation
[Cl:1][c:2]1[c:3]2[cH:4][c:5]([C:13]([F:14])([F:15])[F:16])[nH:6][c:7]2[cH:8][cH:9][c:10]1[C:11]#[N:12].[F:17][C:18]([c:19]1[cH:20][c:21](-[c:29]2[n:30][c:31]([CH2:34][Cl:35])[n:32][o:33]2)[cH:22][c:23]([C:25]([F:26])([F:27])[F:28])[cH:24]1)([F:36])[F:37]>>[Cl:1][c:2]1[c:3]2[cH:4][c:5]([C:13]([F:14])([F:15])[F:16])[n:6]([CH2:34][c:31]3[n:30][c:29](-[c:21]4[cH:20][c:19]([C:18]([F:17])([F:36])[F:37])[cH:24][c:23]([C:25]([F:26])([F:27])[F:28])[cH:22]4)[o:33][n:32]3)[c:7]2[cH:8][cH:9][c:10]1[C:11]#[N:12]

Participants

3

Reactant 2

HCID 27809575-[3,5-Bis(trifluoromethyl)phenyl]-3-(chloromethyl)-1,2,4-oxadiazoleHCID 674056604-chloro-2-(trifluoromethyl)-1H-indole-5-carbonitrile

Product 1

HCID 578001071-({5-[3,5-bis(Trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-4-chloro-2-(trifluoromethyl)-1H-indole-5-carbonitrile

Sources & evidence

ORD record
ord-61fb77d62a9a4c15853d5fa7dc8c4301
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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