6-(chloromethyl)-4-(3-methoxypropyl)-2H-benzo[b][1,4]oxazin-3(4H)-one → tert-Butyl 3-[4-(3-methoxypropyl)-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-4-[4-(3-phenoxypropoxy)phenyl]piperidine-1-carboxylate
Reaction equation
[Cl:32][CH2:33][c:34]1[cH:35][cH:36][c:37]2[c:38]([cH:49]1)[N:39]([CH2:44][CH2:45][CH2:46][O:47][CH3:48])[C:40](=[O:43])[CH2:41][O:42]2.[OH:1][CH:2]1[CH2:3][N:4]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:5][CH2:6][CH:7]1[c:8]1[cH:9][cH:10][c:11]([O:14][CH2:15][CH2:16][CH2:17][O:18][c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[cH:12][cH:13]1>>[O:1]([CH:2]1[CH2:3][N:4]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:5][CH2:6][CH:7]1[c:8]1[cH:9][cH:10][c:11]([O:14][CH2:15][CH2:16][CH2:17][O:18][c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[cH:12][cH:13]1)[CH2:33][c:34]1[cH:35][cH:36][c:37]2[c:38]([cH:49]1)[N:39]([CH2:44][CH2:45][CH2:46][O:47][CH3:48])[C:40](=[O:43])[CH2:41][O:42]2Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-11f38f3a2dd74b87a4344d0d085596fe
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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