Acetonitrile → N-(3-{8-(2,6-difluorophenyl)-7-oxo-2-[(2,2,6,6-tetramethyl-4-piperidinyl)amino]-7,8-dihydropyrido[2,3-d]pyrimidin-4-yl]-4-methylphenyl)-3-thiophenecarboxamide
Reaction equation
[CH3:39][C:40]1([CH3:49])[NH:41][C:42]([CH3:47])([CH3:48])[CH2:43][CH:44]([NH2:46])[CH2:45]1.[CH3:50][C:51]#[N:52].[F:1][c:2]1[c:3](-[n:9]2[c:10](=[O:38])[cH:11][cH:12][c:13]3[c:14]2[n:15][c:16]([S:34]([CH3:35])(=[O:36])=[O:37])[n:17][c:18]3-[c:19]2[cH:20][c:21]([NH:26][C:27](=[O:28])[c:29]3[cH:30][s:31][cH:32][cH:33]3)[cH:22][cH:23][c:24]2[CH3:25])[c:4]([F:8])[cH:5][cH:6][cH:7]1>>[F:1][c:2]1[c:3](-[n:9]2[c:10](=[O:38])[cH:11][cH:12][c:13]3[c:14]2[n:15][c:16]([NH:46][CH:44]2[CH2:43][C:42]([CH3:47])([CH3:48])[NH:41][C:40]([CH3:39])([CH3:49])[CH2:45]2)[n:17][c:18]3-[c:19]2[cH:20][c:21]([NH:26][C:27](=[O:28])[c:29]3[cH:30][s:31][cH:32][cH:33]3)[cH:22][cH:23][c:24]2[CH3:25])[c:4]([F:8])[cH:5][cH:6][cH:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-04840279092f406c829ccf1fc2a9092f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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