5-bromo-N-(1-hydroxy-2-methylpropan-2-yl)pyridine-3-sulfonamide → 5-[5-(4-Chloro-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-pyridine-3-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide

HRID 1238472Notes

Reaction equation

HRID 1238472 reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([cH:12][cH:13]2)[n:14][cH:15][c:16]3[C:17]#[CH:18])[cH:6][cH:7]1.[OH:19][CH2:20][C:21]([CH3:22])([CH3:23])[NH:24][S:25](=[O:26])(=[O:27])[c:28]1[cH:29][n:30][cH:31][c:32]([Br:34])[cH:33]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([cH:12][cH:13]2)[n:14][cH:15][c:16]3[C:17]#[C:18][c:32]2[cH:31][n:30][cH:29][c:28]([S:25]([NH:24][C:21]([CH2:20][OH:19])([CH3:22])[CH3:23])(=[O:26])=[O:27])[cH:33]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 602093435-bromo-N-(1-hydroxy-2-methylpropan-2-yl)pyridine-3-sulfonamideHCID 866080485-(4-Chloro-phenyl)-3-ethynyl-pyrazolo[1,5-a]pyrimidine

Product 1

HCID 670004045-[5-(4-Chloro-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-pyridine-3-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide

Sources & evidence

ORD record
ord-f8ef8f8143424504bbb84f6520cf6e28
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…