Ammonia → 1-(4-Aminomethylphenyl)-3-(3-hydroxy-3-phenylpropyl)-4-(4-methoxyphenyl)azetidin-2-one

HRID 123852Notes

Reaction equation

HRID 123852 reaction equation
[CH3:35][CH2:36][OH:37].[H:33][H:34].[NH3:32].[OH:1][CH:2]([CH2:3][CH2:4][CH:5]1[CH:6]([c:18]2[cH:19][cH:20][c:21]([O:24][CH3:25])[cH:22][cH:23]2)[N:7]([c:10]2[cH:11][cH:12][c:13]([C:14]#[N:15])[cH:16][cH:17]2)[C:8]1=[O:9])[c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1>>[OH:1][CH:2]([CH2:3][CH2:4][CH:5]1[CH:6]([c:18]2[cH:19][cH:20][c:21]([O:24][CH3:25])[cH:22][cH:23]2)[N:7]([c:10]2[cH:11][cH:12][c:13]([CH2:14][NH2:15])[cH:16][cH:17]2)[C:8]1=[O:9])[c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1

Participants

5

Reactant 4

HCID 222AmmoniaHCID 702EthanolHCID 226675944-[3-(3-Hydroxy-3-phenylpropyl)-2-(4-methoxyphenyl)-4-oxoazetidin-1-yl]benzonitrileHCID 178418361HCID 178418361, compound

Product 1

HCID 159224861-(4-Aminomethylphenyl)-3-(3-hydroxy-3-phenylpropyl)-4-(4-methoxyphenyl)azetidin-2-one

Sources & evidence

ORD record
ord-7e824938d4ac4d26b388be45c6657d7c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…