4-Fluorophenylboronic acid → N-[4-bromo-3-(4-fluorophenyl)-1,2-thiazol-5-yl]-2-methylcyclopropane-1-carboxamide

HRID 1238521Notes

Reaction equation

HRID 1238521 reaction equation
[Br:11][c:12]1[n:13][s:14][c:15]([NH:18][C:19](=[O:20])[CH:21]2[CH:22]([CH3:24])[CH2:23]2)[c:16]1[Br:17].[OH:1][B:2]([OH:3])[c:4]1[cH:5][cH:6][c:7]([F:8])[cH:9][cH:10]1>>[c:4]1(-[c:12]2[n:13][s:14][c:15]([NH:18][C:19](=[O:20])[CH:21]3[CH:22]([CH3:24])[CH2:23]3)[c:16]2[Br:17])[cH:5][cH:6][c:7]([F:8])[cH:9][cH:10]1

Participants

3

Reactant 2

HCID 2856454-Fluorophenylboronic acidHCID 67180158N-(3,4-dibromo-1,2-thiazol-5-yl)-2-methylcyclopropane-1-carboxamide

Product 1

HCID 67180229N-[4-bromo-3-(4-fluorophenyl)-1,2-thiazol-5-yl]-2-methylcyclopropane-1-carboxamide

Sources & evidence

ORD record
ord-abdbe371556645608ceeac6545306b36
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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