Imidazole → 7-{[Tert-butyl(dimethyl)silyl]oxy}-5,6,7,8-tetrahydronaphthalen-1-amine
Reaction equation
[C:13]([CH3:14])([CH3:15])([CH3:16])[Si:17]([CH3:18])([CH3:19])[Cl:20].[Cl:26][CH2:27][Cl:28].[NH2:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:11]1[CH2:10][CH:9]([OH:12])[CH2:8][CH2:7]2.[nH:21]1[cH:22][cH:23][n:24][cH:25]1>>[NH2:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:11]1[CH2:10][CH:9]([O:12][Si:17]([C:13]([CH3:14])([CH3:15])[CH3:16])([CH3:18])[CH3:19])[CH2:8][CH2:7]2Participants
5
Sources & evidence
- ORD record
- ord-57752ed7f68048e296c826708d68bd17
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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