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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1238721Generated: October 26, 2026

Dimethylformamide → 1'-[(6-Chloro-1H-indol-3-yl)carbonyl]spiro[isoindole-1,4'-piperidin]-3(2H)-one

https://huagongshe.com/reaction/1238721

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
Reactant1-Chloro-N,N-2-trimethylpropenylamineHCID 640792—
ReactantSpiro[isoindoline-1,4'-piperidin]-3-oneHCID 15548169—
Reactant6-chloro-1H-indole-3-carboxylic acidHCID 18453235—
Product1'-[(6-Chloro-1H-indol-3-yl)carbonyl]spiro[isoindole-1,4'-piperidin]-3(2H)-oneHCID 59657503—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-24c9ef03ab6a4abaa6c8dd89e6648a43
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)