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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1238722Generated: October 25, 2026

Dichloromethane → methyl 4-[4-[[3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-carbonyl]amino]phenyl]butanoate

https://huagongshe.com/reaction/1238722

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantDiphenylphosphinic chlorideHCID 73910—
ReactantDiisopropylethylamineHCID 81531—
ReactantMethyl 4-aminobenzenebutanoateHCID 88628—
Reactant3-(3-Chloro-2-fluoro-phenyl)-4-(4-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2-dimethyl-propyl)-pyrrolidine-2-carboxylic acidHCID 66688251—
Productmethyl 4-[4-[[3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-carbonyl]amino]phenyl]butanoateHCID 178500101—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-cb70dd1fd4c84f9fa000d93d4e1d551f
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)