1-Butanol → (4,4-Diphenylpiperidin-1-yl)acetonitrile

HRID 1238757Notes

Reaction equation

HRID 1238757 reaction equation
[C:23](=[O:24])([O-:25])[O-:26].[CH2:31]([OH:32])[CH2:33][CH2:34][CH3:35].[CH2:36]1[O:37][CH2:38][CH2:39][O:40][CH2:41]1.[Cl:19][CH2:20][C:21]#[N:22].[I-:30].[K+:27].[K+:28].[K+:29].[c:1]1([C:7]2([c:13]3[cH:14][cH:15][cH:16][cH:17][cH:18]3)[CH2:8][CH2:9][NH:10][CH2:11][CH2:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([C:7]2([c:13]3[cH:14][cH:15][cH:16][cH:17][cH:18]3)[CH2:8][CH2:9][N:10]([CH2:20][C:21]#[N:22])[CH2:11][CH2:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

8

Reactant 7

HCID 2631-ButanolHCID 813Potassium Cation3×HCID 7856ChloroacetonitrileHCID 19660Carbonate IonHCID 30165Iodide IonHCID 312751,4-DioxaneHCID 28232394,4-Diphenylpiperidine

Product 1

HCID 23004060(4,4-Diphenylpiperidin-1-yl)acetonitrile

Sources & evidence

ORD record
ord-0eb92ead36f848e89edfd6d19b4e4eae
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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