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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1238846Generated: November 1, 2026

1,2-Dichloroethane → 2-[5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-[1-(3,3-difluoroazetidin-1-yl)butan-2-yl]-3-methyl-2-oxopiperidin-3-yl]acetic acid

https://huagongshe.com/reaction/1238846

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantHydrochloric AcidHCID 313—
ReactantSodium ionHCID 923—
ReactantTriacetoxyborohydrideHCID 2724942—
Reactant3,3-DifluoroazetidineHCID 2758248—
Reactant2-[5-(3-Chlorophenyl)-6-(4-chlorophenyl)-3-methyl-2-oxo-1-(1-oxobutan-2-yl)piperidin-3-yl]acetic acidHCID 76834785—
Product2-[5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-[1-(3,3-difluoroazetidin-1-yl)butan-2-yl]-3-methyl-2-oxopiperidin-3-yl]acetic acidHCID 68001013—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-6e54448d92404967b3f09d073ffa62cc
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)