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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 123888Generated: October 26, 2026

1-(2-Hydroxyethyl)-2-pyrrolidinone → 2-(2-Oxopyrrolidin-1-yl)ethyl 3-(2-tert.-butoxy-2-oxoethyl)-4-(4-cyanophenyl)-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrimidine-5-carboxylate

https://huagongshe.com/reaction/123888

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Hydroxyethyl)-2-pyrrolidinoneHCID 76980—
Reactanttert.-Butyl [6-(4-cyanophenyl)-5-(1H-imidazol-1-ylcarbonyl)-4-methyl-2-oxo-3-[3-(trifluoromethyl)phenyl]-3,6-dihydropyrimidin-1(2H)-yl]acetateHCID 59684795—
Product2-(2-Oxopyrrolidin-1-yl)ethyl 3-(2-tert.-butoxy-2-oxoethyl)-4-(4-cyanophenyl)-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrimidine-5-carboxylateHCID 59684855—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-cda089aae106451da50f4546651da730
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)