tert-Butyl carbamate → tert-butyl [3-cyclopropyl-4-(4-fluorophenyl)-2,2-dimethyl-2H-chromen-7-yl]carbamate

HRID 1238947Notes

Reaction equation

HRID 1238947 reaction equation
[C:24]([NH2:25])([O:26][C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:10]([cH:11]1)[O:9][C:8]([CH3:12])([CH3:13])[C:7]([CH:14]1[CH2:15][CH2:16]1)=[C:6]2[c:17]1[cH:18][cH:19][c:20]([F:23])[cH:21][cH:22]1>>[c:2]1([NH:25][C:24]([O:26][C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31])[cH:3][cH:4][c:5]2[c:10]([cH:11]1)[O:9][C:8]([CH3:12])([CH3:13])[C:7]([CH:14]1[CH2:15][CH2:16]1)=[C:6]2[c:17]1[cH:18][cH:19][c:20]([F:23])[cH:21][cH:22]1

Participants

3

Reactant 2

HCID 77922tert-Butyl carbamateHCID 594430267-chloro-3-cyclopropyl-4-(4-fluorophenyl)-2,2-dimethyl-2H-chromen

Product 1

HCID 59443016tert-butyl [3-cyclopropyl-4-(4-fluorophenyl)-2,2-dimethyl-2H-chromen-7-yl]carbamate

Sources & evidence

ORD record
ord-5a861c889f714da4bbafe435c5a1eb4c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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