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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1239115Generated: October 25, 2026

Chloride → 1-(5-Chloropyridin-2-yl)-1-(3-fluoro-5-(trifluoromethyl)phenyl)-2-phenylethanamine

https://huagongshe.com/reaction/1239115

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantChlorotrimethylsilaneHCID 6397—
ReactantTetrahydrofuranHCID 8028—
Reactant3-Bromo-5-fluorobenzotrifluorideHCID 2736323—
Reactant5-Chloro-2-cyanopyridineHCID 3833942—
ReactantButyllithiumHCID 178418339—
ReactantHCID 178507042HCID 178507042—
Product1-(5-Chloropyridin-2-yl)-1-(3-fluoro-5-(trifluoromethyl)phenyl)-2-phenylethanamineHCID 59134573—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-3866ba35e5f8453c87d4d5d37b7319ee
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)