3,3-Dimethyl-1-(3-nitropyridin-2-yl)-2,3-dihydro-1H-indole → 2-(3,3-Dimethylindolin-1-yl)pyridin-3-amine

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Reaction Steps

To a solution of 4a (30 mg, 0.111 mmol) in MeOH was added 10% Pd/C (10 mg). The reaction mixture was stirred at rt under H2 for 2 h. The catalyst was filtered through a cake of Celite® and the filtrate was evaporated under reduced pressure to afford 4b (20 mg, 76%) as a yellowish powder. MS (ES) m/z 240 [M+H]+.

Provenance & Evidence