1,4-Dioxane → N-(3-(4-Fluoro-phenyl)-pyridin-2-yl)-N'-ethoxycarbonyl-thiourea

HRID 1239256Notes

Reaction equation

HRID 1239256 reaction equation
[CH2:15]([CH3:16])[O:17][C:18](=[O:19])[N:20]=[C:21]=[S:22].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([NH2:14])[n:10][cH:11][cH:12][cH:13]2)[cH:6][cH:7]1.[O:23]1[CH2:24][CH2:25][O:26][CH2:27][CH2:28]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([NH:14][C:21]([NH:20][C:18]([O:17][CH2:15][CH3:16])=[O:19])=[S:22])[n:10][cH:11][cH:12][cH:13]2)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 312751,4-DioxaneHCID 85320Ethyl isothiocyanatoformateHCID 463118843-(4-Fluoro-phenyl)-pyridin-2-ylamine

Product 1

HCID 86656216N-(3-(4-Fluoro-phenyl)-pyridin-2-yl)-N'-ethoxycarbonyl-thiourea

Sources & evidence

ORD record
ord-aecfde6c23784f41945d1243c1d2e890
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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