1-methyl-1H-1,3-benzodiazole-2-carbaldehyde → 6-[2-(3-Chloro-4-cyclopropylmethoxy-phenyl)-ethyl]-6-cyclopentyl-4-hydroxy-3-(1-methyl-1H-benzoimidazol-2-ylmethyl)-5,6-dihydro-pyran-2-one

HRID 1239301Notes

Reaction equation

HRID 1239301 reaction equation
[CH3:54][n:55]1[c:56]([CH:64]=[O:65])[n:57][c:58]2[c:59]1[cH:60][cH:61][cH:62][cH:63]2.[CH3:66][c:67]1[cH:68][c:69]([CH3:70])[n:71]2[n:72][c:73]([CH:74]=[O:75])[n:76][c:77]2[n:78]1.[Cl:1][c:2]1[cH:3][c:4]([CH2:13][CH2:14][C:15]2([CH:23]3[CH2:24][CH2:25][CH2:26][CH2:27]3)[CH2:16][C:17](=[O:22])[CH2:18][C:19](=[O:21])[O:20]2)[cH:5][cH:6][c:7]1[O:8][CH2:9][CH:10]1[CH2:11][CH2:12]1.[Cl:28][c:29]1[cH:30][c:31]([CH2:32][CH2:33][C:34]2([CH:35]3[CH2:36][CH2:37][CH2:38][CH2:39]3)[O:40][C:41](=[O:42])[CH2:43][C:44](=[O:45])[CH2:46]2)[cH:47][cH:48][c:49]1[O:50][CH:51]([CH3:52])[CH3:53]>>[Cl:1][c:2]1[cH:3][c:4]([CH2:13][CH2:14][C:15]2([CH:23]3[CH2:24][CH2:25][CH2:26][CH2:27]3)[CH2:16][C:17]([OH:22])=[C:18]([CH2:64][c:56]3[n:55]([CH3:54])[c:59]4[c:58]([n:57]3)[cH:63][cH:62][cH:61][cH:60]4)[C:19](=[O:21])[O:20]2)[cH:5][cH:6][c:7]1[O:8][CH2:9][CH:10]1[CH2:11][CH2:12]1

Participants

5

Reactant 4

HCID 7620841-methyl-1H-1,3-benzodiazole-2-carbaldehydeHCID 167287396-[2-(3-Chloro-4-isopropoxy-phenyl)ethyl]-6-cyclopentyl-tetrahydropyran-2,4-dioneHCID 236352265,7-Dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carbaldehydeHCID 587626706-[2-(3-Chloro-4-cyclopropylmethoxy-phenyl)-ethyl]-6-cyclopentyl-dihydro-pyran-2,4-dione

Product 1

HCID 587623816-[2-(3-Chloro-4-cyclopropylmethoxy-phenyl)-ethyl]-6-cyclopentyl-4-hydroxy-3-(1-methyl-1H-benzoimidazol-2-ylmethyl)-5,6-dihydro-pyran-2-one

Sources & evidence

ORD record
ord-46ee37114a0b4fb9a9307f0ba8810a2e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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